In the NFL, winning almost always comes with a cost, in one way or another. Green Bay’s win over the 49ers yesterday was no exception, as the Packers lost two of their best defenders in the process.

According to Tom Pelissero of the Green Bay Press-Gazette, CB Al Harris and DE/LB Aaron Kampman are finished for the remainder of the season after they both suffered major knee injuries. Both will have surgery to repair the damage, and will be placed on the injured reserve list some time this week.

While Kampman has struggled tremendously in adjusting to the new 3-4 style of play being employed in Green Bay this season, Harris has always been a reliable cover corner, capable of playing the man-to-man defense the Packers love to use. His loss pushes CB Tramon Williams into the starting role, with Kampman’s replacement still being determined by head coach Mike McCarthy and his coaching staff.