Julen Lopetegui's side now boast a goal difference advantage of 17 over the Italians who need just a point from their game against Macedonia to guarantee a top-two finish and a place in the play-offs.
Wales are in a similar position, so an electric atmosphere is expected at the City of Cardiff Stadium, but Ireland goalkeeper Darren Randolph says it will be a night for cool heads.
Chris Coleman (Wales): "We're on unsafe ground if we go in with a game plan of trying to soak the pressure up for 90 minutes".
"We are too good to do that".
"I feel over the last three games with Southampton I didn't really have many chances and on Friday I got three but they just wouldn't go in for me". That's the way it's set up. "You want to stay in the game as long as possible".
Wales and Ireland have shut each other out over their past two clashes.
Republic captain Seamus Coleman had his leg broken by a challenge from Wales defender Neil Taylor in the goalless draw and has not played football since.
The match will be under much scrutiny not only because of the high stakes. Whatever game plan we have we will utilise it the best we can. "We were all absolutely devastated at what happened".
Bale's goals fired Wales to last summer's European Championships, a first major tournament since the 1958 World Cup.
Republic of Ireland team is boosted by the return of players Robbie Brady and James McClean who were in the suspension but Shane Long is ruled out of the squad due to the injury.
Spain, the 2010 world champions, secured top spot in Group G after they stormed to a 3-0 win over Albania.
1850: Wales have made just one change from Friday night's win in Georgia with Hal Robson-Kanu selected ahead of Sam Vokes as the central forward option. One would not be enough but would still end Ireland's own play-off dream.
The Route 91 Harvest country music festival, where the mass shooting took place, was located about 1,100 feet from the tanks. Minutes after the shooting began, a hotel security guard showed up outside his suite and Paddock shot him in the leg.
A lot of good teams won't go to that World Cup , so we are pleased but still know there is room for improvement. He could play in midfield, on the wing, at No 10 or even as a wing-back - you need players that are versatile.
Many hotels on the Las Vegas strip close to the scene were placed on police lockdown and parts of Las Vegas Boulevard were shut. Police said Paddock killed himself before a SWAT team breached his hotel room overlooking the country music venue.
The American got the job done with a triangle joke and insists he can immobilise 155lb king McGregor on the ground as well. Then, in the final stanza, he delivered something to satisfy more than just the diehards.
Patrick has started every game for the No. 5 Bulldogs this season and is tied for third on the team with 17 total tackles. Players receive a four-game suspension following a second marijuana violation, according to the UGA football handbook.
Understand, the Justice Department under Sessions is already reversing numerous positions it held under President Barack Obama. However, portions of the memo seem to set things up for people to use religious freedom as a basis for LGBTI discrimination.
Storm surge threatened low-lying communities in southeast Louisiana, eastward to the Alabama fishing village of Bayou la Batre. According to the Associated Press , Nate has been responsible for 22 deaths in Central America, mainly due to flooding.
But on Sunday, a sea of Spanish flags, interspersed with some Catalan and European Union flags, dominated Barcelona's boulevards. At the same time, according to Rahoy, the Spanish authorities do not need any mediation to settle the situation in Catalonia.
A tweet showing pictures of the jug and a customized carrying case garnered more than 342,000 likes and 142,000 re-tweets. Customers can't go through the drive-thru for the beloved sauce - they have to dine in.
In Cairo, an army helicopter dropped hundreds of Egyptian flags on thousands of fans gathered at the city's iconic Tahrir square. Fans honking vehicle horns and waving Egypt's red, white and black flags took the streets across the country.
Third-seeded Elina Svitolina of the Ukraine posted a 6-4, 6-2 win over Australian Ashleigh Barty in their second-round match. Simona Halep is the first Romanian to achieve the world No. 1 ranking since the system was implemented in 1975.
Vegas Shooter Booked Hotel Rooms Overlooking Lollapalooza
That said, a senior law enforcement official said that hotels in the vicinity typically have an obstructed view, if one at all. Investigators are still trying to determine a motive for the Las Vegas shooting and Paddock's whereabouts the last few months.
Baltimore Ravens vs. Oakland Raiders: 3 key matchups
Staley has written for Bleacher Report, the Miami Herald and the Palm Beach Post and is a reporter for Pro Player Insiders. To extend even further, only 15 teams that have fallen three games under.500 in Week 5 or later made the postseason.
Rosier rallies No 13 Miami to 24-20 win over Florida State
For some reason, with just two games behind each team, a consensus had been formed that Miami was good and Florida State was not. On the ensuing possession, he converted a third-and-10 before being intercepted by Stanford Samuels III two plays later.