Generic Drug Gets 6000% Price Increase From Marathon
Feb 14, 2017, 00:14
In an interview, Marathon CFO Babar Ghias noted the company will likely receive much less in net revenue than the list price, after providing discounts to government insurers and financial support to patients who can not afford the medication. This is the first corticosteroid approved by the FDA to treat patients who have Duchenne muscular dystrophy.
The two congressmen, who have previously eyed Valeant, Turing, and Mylan, among other pharma firms, on Monday wrote a letter to Marathon Pharmaceuticals seeking answers about its newly approved $89,000 treatment for Duchenne muscular dystrophy. Emflaza is a corticosteroid that works by decreasing inflammation and reducing the activity of the immune system.
"This is the first treatment approved for a wide range of patients with Duchenne muscular dystrophy, " said Billy Dunn, MD, director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research.
Marathon's chief financial officer defended the new price tag for deflazacort by claiming it is "modestly priced for an orphan drug".
Deflazacort has always been used off-label for DMD treatment, but until now hadn't been approved to treat the condition.
Sanders and Cummings noted that the drug has been imported by patients in the US for "decades".
A USA Today report reveals the drug, a steroid known as deflazacort, will cost patients a whopping $89,000 per year, almost 70 times higher than buying the drug in other countries. Marathon, the company that owns Emflaza, did not invent deflazacort, and patients have been able to import it cheaply for for years since it hadn't been approved in the US.
The U.S. Food and Drug Administration is now approved Emflaza (deflazacort), an old steroid treatment, long accessible outside the United States. Sarepta's drug treats a subset of DMD patients representing about 13% of the total. It improves muscle strength.
Announcing the approval, the FDA said it granted the application fast track designation and priority review. An overall stability in average muscle strength was maintained through the end of study at week 52 in the deflazacort-treated patients. Patients lack a protein called dystrophin that's essential for healthy muscle, and eventually lose the ability to walk, stand and breathe. This is the 9th time that the FDA grants the pediatric disease priority voucher.
Emflaza side effects are similar to other corticosteroids, such as puffiness of the face, weight gain, increased appetite, infection of the upper respiratory tract, fequent urination, stomach fat, cough, and unwanted hair growth.
North Korea has confirmed that it "successfully" fired a ballistic missile on Sunday in a test supervised by leader Kim Jong-un. The missile is said to have been launched at 07:55 local time (22:55 GMT Saturday), and flew east towards the Sea of Japan.
As foreign minister, Mr Steinmeier often acted as a voice of reason, bridging gaps and bringing people together. Steinmeier, who was formerly a foreign minister, is from the center-left Christian Democratic Party.
MUMBAI: The world's heaviest woman , Eman Ahmed from Egypt, was admitted to Mumbai's Saifee Hospital early on Saturday. But today she has been lifted by crane into a specially adapted surgery in a hospital in the Indian city of Mumbai .
Mr Fankhauser declined to comment on his pay plans, which he said were drawn up by the group's remuneration committee. "We remain cautious about the rest of the year, given the uncertain political and economic outlook".
French politicians are allowed to hire family members as aides as long as they actually do the jobs for which they are paid. The paper says she already had a new aide job, arranged at Fillon's request, working for the lawmaker who replaced him.
The young pitcher, who signed a $23 million, five-year deal shortly before opening day in 2015, was pronounced dead at the scene. Duffy, it should be noted, has never thrown more than 200 innings in a season and struggled in the second half previous year .
I had a bad start, he quickly broke me at the beginning of the match. "Both of us played really well from the baseline". Montpellier is the second career ATP title for Zverev who is projected to rise inside the ATP top 20 next week.
NCAA Tournament chairman Mark Hollis will be on the show with host Greg Gumbel and analysts Clark Kellogg and Seth Davis. The NCAA Tournament Selection Committee released its first edition of the top 16 seeds for March Madness on Saturday.
Neighbouring Pakistan was also hit by severe weather, with at least 13 people killed in the northwest by avalanches or heavy rain. The power supply was also interrupted in some areas of the capital.
Properties lost in NSW bushfires
Anyone east of Cassilis has been advised to leave now towards Merriwa, and anyone north of Ulan should move south towards Mudgee. FIRE RACING: The Rural Fire Service warned strong winds in the region would enable the fire in the Leadville to spread quickly.
Michael Kors Sales Hurt By Dismal Store Traffic
The average true range of the stock is observed at 1.11 and the relative strength index of the stock is recorded at 39.43. Michael Kors Holdings Limited's revenue for the quarter was down 3.7% compared to the same quarter a year ago .
Sasikala to be next Tamil Nadu CM: Events as they unfolded
In December a year ago , four state ministers had asked Sasikala to become the Chief Minister, besides AIADMK General Secretary. The Chief Minister's Office, the official said, is preparing to call a conference of all district collectors and police chiefs.